By Jayant Narlikar
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Additional resources for A Journey Through The Universe
The success of disease modifying antirheumatic drugs (DMARD) and more recently the advent of biologic response-modifying drugs has increased the interest in the imaging modalities for evaluating the disease progression. These drugs are not only very expensive but are also potentially toxic necessitating their judicious use. The presence of erosions in early disease serves as a diagnostic marker for RA and is a sign of poor prognosis, signaling potentially aggressive disease (Van der Heijde et al.
An international survey published in 2006 (Groves et al. 2006) of hospital practices revealed marked inconsistency in acute wrist fracture imaging protocols, which the authors believe are likely to be multifactorial but also probably reflected a deficiency in scientific evidence regarding the best practice for imaging occult wrist fractures. Moreover, practices will vary according to local expertise and availability of the different modalities operating within the constraints of individual healthcare local resources.
But if a primary bone tumor is suspected then work-up should proceed with MR imaging to evaluate the intra and extraosseous extent of tumor. Where it may be difficult to discern the pattern of bone destruction, it is recommended that CT be performed following radiography. This will help determine the pattern of bone destruction and periosteal new bone formation and to assess for the presence of matrix mineralization. Osteoid osteoma is a benign bone tumor representing approximately 10 % of all benign bone tumors.
A Journey Through The Universe by Jayant Narlikar